Anticoagulation management during pulmonary endarterectomy with cardiopulmonary bypass and deep hypothermic circulatory arrest.

CONCLUSION: This study shows a wide variation in individual heparin sensitivity in patients undergoing pulmonary endarterectomy with deep hypothermic circulatory arrest. Although activated clotting time-guided anticoagulation management may underestimate the level of anticoagulation and consequently result in a less profound inhibition of hemostatic activation, this study lacked power to detect adverse outcomes.
PMID: 32522088 [PubMed - as supplied by publisher]

Source: Perfusion - June 9, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Veerhoek D, van Barneveld LJ, Haumann RG, Kamminga SK, Vonk AB, Boer C, Symersky P Tags: Perfusion Source Type: research