The Effects of Sigma‐1 Receptor Selective Ligands on Muscarinic Receptor Antagonist Induced Cognitive Deficits in Mice

Conclusions and ImplicationsThe sigma‐1 receptor selective compound such as LS‐1‐137 may represent a novel candidate cognitive enhancer for the treatment of cholinergic muscarinic‐dependent cognitive deficits.

Source: British Journal of Pharmacology - January 9, 2015 Category: Drugs & Pharmacology Authors: Maninder Malik, Claudia Rangel‐Barajas, Nathalie Sumien, Chang Su, Meharvan Singh, Zhenglan Chen, Ren‐Qi Huang, Johann Meunier, Tangui Maurice, Robert H. Mach, Robert R. Luedtke Tags: Research Paper Source Type: research