Early cognitive decline after bilateral subthalamic deep brain stimulation in Parkinson's disease patients with GBA mutations

Subthalamic nucleus deep brain stimulation (STN-DBS) has demonstrated its efficacy on motor complications in advanced Parkinson's disease (PD) but does not modify disease progression. Genetic forms of PD have been associated with different cognitive progression profiles.

Source: Parkinsonism and Related Disorders - June 7, 2020 Category: Neurology Authors: Graziella Mangone, Samir Bekadar, Florence Cormier-Dequaire, Khadija Tahiri, Arlette Welaratne, Virginie Czernecki, Fanny Pineau, Carine Karachi, Anna Castrioto, Frank Durif, Christine Tranchant, David Devos, St éphane Thobois, Wassilios Meissner, Maria Source Type: research