There's No I in Team: Cellular Crosstalk Enhances In Vitro Cardiac Maturation.
There's No I in Team: Cellular Crosstalk Enhances In Vitro Cardiac Maturation.
Cell Stem Cell. 2020 Jun 04;26(6):799-801
Authors: Mills RJ, Hudson JE
Abstract
Organoids and microtissues offer the unique opportunity to dissect cell-cell interactions in an organ-specific context without confounding effects of organ failure or organism viability. In a study in this issue of Cell Stem Cell, Giacomelli et al. (2020) add human cardiac fibroblasts into cardiac microtissues and reveal striking fibroblast-endothelial-cardiomyocyte crosstalk that promotes advanced cardiomyocyte maturation.
PMID: 32502399 [PubMed - as supplied by publisher]
Source: Cell Stem Cell - Category: Stem Cells Authors: Mills RJ, Hudson JE Tags: Cell Stem Cell Source Type: research