Cancers, Vol. 12, Pages 1484: TGF α Promotes Chemoresistance of Malignant Pleural Mesothelioma

Conclusions: Our data show that TGFα but not its receptor EGFR is a key factor in resistance to MPM chemotherapy. This observation may contribute to casting light on the promising but still controversial role of EGFR signaling in MPM therapy.

Source: Cancers - June 5, 2020 Category: Cancer & Oncology Authors: Staumont Jamakhani Costa Vandermeers Sriramareddy Redout é Mascaux Delvenne Hubert Safari Willems Tags: Article Source Type: research