LP44 (4-[2-(methylthio)phenyl]- N -(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide) exerts anti-ulcer effects via 5-hydroxytryptamine receptor  7 activation on indomethacin-induced gastric ulcers in rats

ConclusionThe study suggested that activation of 5-HT7 receptor showed a significant anti-ulcerogenic effect in the indomethacin-induced gastric ulcer model.

Source: Inflammopharmacology - June 4, 2020 Category: Drugs & Pharmacology Source Type: research