Use of pleural cryobiopsy for tissue culture specimens: a case report

We present the case of a 43 ‐year‐old man with suspected tuberculous pleurisy (TP). Thoracoscopy under local anaesthesia showed the entire pleura with scattered nodules. Nodules were biopsied by conventional biopsy forceps, but the tissue sample was small, so a cryobiopsy was performed. Histological analysis of the convent ional biopsy forceps and cryobiopsy specimen showed inflammation with lymphocytes and caseating granulomas. Tissue culture of conventional biopsy forceps was positive forMycobacterium tuberculosis, and all sensitivity tests were positive. But, the tissue culture of the cryobiopsy sample was negative. There is a possibility that cryobiopsy is not useful for tissue culture for TP. AbstractA 43 ‐year‐old man presented with cough. His chest X‐ray showed a left‐sided pleural effusion. We suspected tuberculous pleurisy (TP), and thoracoscopy under local anaesthesia was performed. It showed entire pleura with scattered nodules. Nodules were biopsied by conventional biopsy forceps, but the tissue sample was small. Therefore, the nodules were biopsied with a cryoprobe. The tissue size obtained was 2 mm by conventional biopsy forceps, and 6 mm at 5 sec by cryobiopsy. Histological analysis of the conventional biopsy forceps and cryobiopsy specimen showed inflammation with lymphoc ytes and caseating granulomas. Tissue culture of conventional biopsy forceps was positive forMycobacterium tuberculosis, and all sensitivity tests were positive. But, the tiss...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research