Reversible and irreversible platelet inhibition by anti platelet agents

Agents which irreversibly inhibit platelets are:
Aspirin
Ticlopidine
Clopidogrel
Prasugrel
In general all these agents except prasugrel are ideally discontinued 5 days prior to intended surgery. Prasugrel is better discontinued 7 days prior, because of slightly different pharmacodynamics profile.
Agents which reversibly inhibit platelets are:
Dipyridamole
Cilostazol
Nonsteroidal anti-inflammatory drugs
Ticagrelor

Source: Cardiophile MD - January 9, 2014 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs