Endocrine–exocrine signals in obesity-associated pancreatic cancer

Nature Reviews Gastroenterology & Hepatology, Published online: 01 June 2020; doi:10.1038/s41575-020-0324-6Obesity is a known risk factor for pancreatic cancer. Now, a new study reports that obesity accelerates early pancreatic cancer development and growth in mice through local perturbations in the pancreatic microenvironment and implicates pancreatic islet-derived cholecystokinin as a driving factor.
Source: Nature Reviews Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research