A mouse model for COVID-19
Small animal models (mice, ferrets, hamsters) are essential for understanding how SARS-CoV-2 causes disease and for pre-clinical evaluation of vaccines and antiviral therapeutics. One promising model has been developed by modifying SARS-CoV-2 so that it binds to murine ACE2. Laboratory mice cannot be infected with SARS-CoV-2 because the viral spike glycoprotein (illustrated) does not bind […]
Source: virology blog - Category: Virology Authors: Vincent Racaniello Tags: Uncategorized ACE2 antiviral coronavirus COVID-19 mouse model SARS-CoV-2 spike glycoprotein vaccine virology viruses Source Type: blogs
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