Characterization of Group I Metabotropic Glutamate Receptors in Rat and Human Adrenal Glands

This study shows the expression of GRM1-8 mRNAs in rat and human adrenal glands and indicates that glutamate, through the activation of mGluRs, may play various physiological roles in the adrenal gland. Furthermore, mGluR1 may be involved in catecholamine biosynthesis by regulating TH, and mGluR5 may affect cortical and medullar hormone levels by regulating microvascular function.
Source: Frontiers in Physiology - Category: Physiology Source Type: research