Plasma oxalate levels in primary hyperoxaluria type I show significant intra-individual variation and do not correlate with kidney function

ConclusionWe conclude that POx has a limited validity as a primary endpoint for clinical studies in PH1 patients with stable kidney function. In addition, it does not correlate to SCr and eGFR in this group of patients.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research