Experiences with legally mandated treatment in patients with schizophrenia: A systematic review of qualitative studies.

CONCLUSIONS: Intervention research has historically focused on clinical outcomes and the quantitative aspects of treatment. Thus, this study provides insight into the qualitative aspects of patients' experiences with legally mandated treatment. Recognizing these opinions and experiences can lead to better attitudes toward treatment for patients with schizophrenia and related psychiatric illnesses. PMID: 32406364 [PubMed - in process]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research

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Authors: Wang YM, Xiao YH, Xie WL Abstract Accumulating evidence implicates that individuals at high-risk of psychosis have already exhibited pathophysiological changes in brain metabolites including glutamate, gamma-Aminobutyric Acid (GABA), N-Acetylaspartate (NAA), creatine (Cr), myo-inositol (MI) and choline (Cho). These changes may contribute to the development of schizophrenia and associate with psychotic genes. However, specific metabolic changes of brain sub-regions in individuals at risk have still been controversial. Thus, the current study aimed to investigate the brain metabolic changes including glutama...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Conclusion, do not visit cardiologists. They will give you heart attacks. No, that’s ridiculous. It’s so mind blowing that anyone even said this, right? It’s just ugh. Obviously, people who are extremely sick and who are at risk of killing themselves get psychiatric care. No kidding. So, yeah, this is, in fact, very dangerous. Gabe: The word bullshit is not big enough. This is the literal equivalent of me saying that I looked at fifty thousand people who went to the hospital in the last year. And you were much more likely to die if you had a hospital admission. Now, I’m talking physical health now. ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness Not Crazy Podcast Psychiatry Treatment Source Type: blogs
Patients with schizophrenia (SCZ) exhibit higher suicide rates than the general population. However, the molecular mechanism remains poorly understood. Tumor necrosis factor (TNF)-alpha polymorphisms have been repeatedly indicated to play a pathogenetic ro...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Conclusion Studies on metacognition in BD are scarce, but the existing literature indicates potential clinical and sociodemographic factors associated with poorer metacognition in the disorder, also suggesting that metacognitive therapeutic interventions may be clinically relevant for the management of BD.
Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
Schizophrenia patients often show impaired facial expression recognition, which leads to difficulties in adaptation to daily life. However, it remains unclear whether the deficit is at the perceptual or higher cognitive level of facial emotion processing. Recent studies have shown that earlier face-evoked event-related potential (ERP) components such as N170 and P100 can effectively distinguish schizophrenia patients from healthy controls; however, findings for later waveforms are ambiguous. To clarify this point, in this study we compared electroencephalographic signals in schizophrenia patients and control subjects durin...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition. The identification of five genes coding for different dopamine receptor subtypes, pharmacologically grouped as D1- (D1 and D5) or D2-like (D2S, D2L, D3, and D4) has allowed the demonstration of differential receptor function in specific neurocircuits. Recent observation on dopamine receptor signaling point at dopamine—glutamate-NMDA neurobiology as the most relevant in schizophrenia and for the development of new therapies. Progress in the chemistry of D1-...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Vincent van Gogh was one of the most influential artists of the Western world, having shaped the post-impressionist art movement by shifting its boundaries forward into abstract expressionism. His distinctive style, which was not valued by the art-buying public during his lifetime, is nowadays one of the most sought after. However, despite the great deal of attention from academic and artistic circles, one important question remains open: was van Gogh’s original style a visual manifestation distinct from his troubled mind, or was it in fact a by-product of an impairment that resulted from the psychiatric illness that...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Increased mortality in schizophrenia runs through all age groups, resulting in a 10- to 20-year shortening of life expectancy compared with the general population. This “mortality gap” may have grown wider over the course of the last several decades (1), mandating renewed efforts by academia and the public health sector to mitigate the current situation. Importantly, two thirds of the excess mortality in schizophrenia is driven by chronic metabolic diseases, in cluding type II diabetes and dyslipidemia, and cardiovascular disease with a multitude of contributing factors, such as unhealthy lifestyles, poor diet,...
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Commentary Source Type: research
It is well established that the different antipsychotics used for schizophrenia symptoms differ substantially in their side effects. However, relatively little is known about the impact of these side effects o...
Source: Annals of General Psychiatry - Category: Psychiatry Authors: Tags: Primary research Source Type: research
J Knee Surg DOI: 10.1055/s-0040-1713756The purpose of this study was to compare the prevalence of mental health conditions among patients undergoing (1) primary total knee arthroplasty (pTKA), (2) septic revision total knee arthroplasty (rTKA), and (3) aseptic revision total knee arthroplasty (TKA). The State Inpatient Databases were queried for all TKAs from 2005 to 2014 yielding 563,144 patients. Patients were separated into the following cohorts: primary, septic revision, and aseptic revision. Diagnoses of any mental health condition and the following specific conditions were compared between the three cohorts: schizoph...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
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