Type 1 Diabetes Mellitus - Risk Factor for Cardiovascular Disease Morbidity and Mortality.

Type 1 Diabetes Mellitus - Risk Factor for Cardiovascular Disease Morbidity and Mortality. Curr Diabetes Rev. 2020 May 10;: Authors: Chalakova T, Yotov Y, Tzotchev K, Galcheva S, Balev B, Bocheva Y, Usheva N, Iotova V Abstract Type 1 diabetes mellitus (T1DM) is a chronic disease which starts early in life and often leads to micro- and macrovascular complications. The incidence of the disease is lower than that of type 2 DM and varies in different countries and ethnical groups, and the etiological and pathogenetic factors are different from T2DM. The aim of this overview is to investigate the effect of T1DM on all-cause mortality and CVD morbidity and mortality. During the last decades the treatment of T1DM has improved the prognosis of the patients. Still, the mortality rates are higher than those of the age- and sex-matched general population. With the prolonged survival, the macrovascular complications and the cardiovascular diseases (CVD) appear as major health problems in the management of patients with T1DM. The studies on the CVD morbidity and mortality in this disease group are sparse but they reveal that T1DM is associated with at least 30% higher mortality. In comparison to healthy people, CVD are more common in T1DM patients and they occur earlier in life. Furthermore, they are a major cause for death and impaired quality of life in T1DM patients. The correlation with the diabetic control and the duration of T1DM is not alw...
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Tags: Curr Diabetes Rev Source Type: research