CD4+ T Cell Responses Mediate Progressive Neurodegeneration in Experimental Ischemic Retinopathy

Retinal ischemic events as a result of occlusion of the ocular vasculature share similar etiologies of central nervous system (CNS) stroke and are among the most common cause of acute and irreversible vision loss in elderly patients. Currently, there is no established treatment, and the condition often leaves patients with seriously impaired vision or blindness. The immune system, particularly T cell-mediated responses, is thought to be intricately involved, but their exact roles remain elusive.

Source: American Journal of Pathology - May 6, 2020 Category: Pathology Authors: Thi Hong Khanh Vu, Huihui Chen, Li Pan, Kin-Sang Cho, Djoeke Doesburg, Eric F. Thee, Nan Wu, Elisa Arlotti, Martine J. Jager, Dong Feng Chen Tags: Regular Article Source Type: research