Individual species and cumulative mixture relationships of 24-hour urine metal concentrations with DNA methylation age variables in older men.

CONCLUSION: Our results add novel evidence that metals detected in urine are associated with increases in biological aging and suggest that these DNA methylation-based measures may be useful for identifying individuals at-risk for diseases related to toxic metal exposures. Further research is necessary to confirm these findings more broadly.
PMID: 32361261 [PubMed - as supplied by publisher]

Source: Environmental Research - April 24, 2020 Category: Environmental Health Authors: Nwanaji-Enwerem JC, Colicino E, Specht AJ, Gao X, Wang C, Vokonas P, Weisskopf MG, Boyer EW, Baccarelli AA, Schwartz J Tags: Environ Res Source Type: research