Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in A β oligomer-treated mice

ConclusionAll these results directly demonstrated the anti-A β oligomer neuroprotective properties of gelsemine, opening a novel perspective for the development of gelsemine-based therapeutics against Aβ-associated neurodegeneration disorders, including AD in particular.

http://link.springer.com/10.1007/s00213-020-05522-y

Source: Psychopharmacology - May 3, 2020 Category: Psychiatry Source Type: research