Incidence and location of lymph node metastases in patients undergoing radical cystectomy for clinical non–muscle invasive bladder cancer: Results from a prospective lymph node mapping study

Conclusions: Routine LND is important in patients with cT1 and cTis-only bladder cancer, but may have limited value in patients with cTa. LNM beyond the boundaries of a standard LND occurred in up to one-third of node-positive patients. In the absence of skip metastases, however, performing a standard LND would correctly identify all node-positive patients. Whether removal of LNM proximal to the common iliac vessels provides a survival benefit remains to be evaluated in future prospective studies.

Source: Urologic Oncology: Seminars and Original Investigations - February 8, 2013 Category: Urology & Nephrology Authors: Harman M. Bruins, Eila C. Skinner, Ryan P. Dorin, Hamed Ahmadi, Hooman Djaladat, Gus Miranda, Jie Cai, Siamak Daneshmand Tags: Abstracts for Online Original Articles and Reviews Source Type: research