Muscone Ameliorates LPS-Induced Depressive-Like Behaviors and Inhibits Neuroinflammation in Prefrontal Cortex of Mice.

This study revealed that muscone could ameliorate LPS-induced depressive-like behaviors by repressing neuroinflammation in the prefrontal cortex of mice caused by its suppression on microglia activation and production of inflammatory cytokines via acting on TLR4 pathway and RAS cascade. PMID: 32345030 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32345030?dopt=Abstract

Source: The American Journal of Chinese Medicine - April 28, 2020 Category: Complementary Medicine Authors: He MC, Shi Z, Qin M, Sha NN, Li Y, Liao DF, Lin FH, Shu B, Sun YL, Yuan TF, Wang YJ, Zhang Y Tags: Am J Chin Med Source Type: research