Inspissated bile syndrome: A rare cause of neonatal cholestasis

A male neonate with a birthweight of 3220  g was transferred to our hospital on the eighth day of life because of progressive neonatal hyperbilirubinemia. His serum total bilirubin and direct bilirubin levels were 22.3 and 0.8 mg/dL, respectively. After 72 h of adequate hydration and phototherapy, these levels had increased to 26.0 and 5 .8 mg/dL, respectively. Other liver function tests were normal except for gamma-glutamyl transpeptidase (234 IU/L) and alkaline phosphatase (230 IU/L). An obstruction of the common bile duct (CBD) due to biliary sludge was demonstrated on abdominal ultrasonography (Fig. 1A and B) at 12 days of age and in follow-up magnetic resonance cholangiopancreatography 3 days after ultrasound examination (Fig. 2).
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Images Source Type: research