Determining molecular predictors of adverse drug reactions with causality analysis based on structure learning.
CONCLUSIONS: The proposed CASTLE model not only performed better in prediction than the baseline SVM but also produced more interpretable results (ie, biological factors responsible for ADRs), which is critical to discovering molecular activators of ADRs.
PMID: 24334612 [PubMed - as supplied by publisher]
Source: Journal of the American Medical Informatics Association - Category: Information Technology Authors: Liu M, Cai R, Hu Y, Matheny ME, Sun J, Hu J, Xu H Tags: J Am Med Inform Assoc Source Type: research
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