Novel Conjugated Quinazolinone-Based Hydroxamic Acids: Design, Synthesis and Biological Evaluation.

CONCLUSION: The resesrch results suggest that some hydroxamic acids could emerge for further evaluation and the results are well served as basics for further design of more potent HDAC inhibitors and antitumor agents.
PMID: 32310052 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - April 18, 2020 Category: Chemistry Authors: Vu TK, Thanh NT, Minh NV, Linh NH, Thao NTP, Nguyen TTB, Hien DT, Chinh LV, Duc TH, Anh LD, Hai PT Tags: Med Chem Source Type: research