Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice.

In conclusion, we demonstrate that pharmacological TGR5 receptor activation stimulates L cells triggering GLP-2 dependent intestinal adaption in mice. PMID: 32308039 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32308039?dopt=Abstract

Source: Am J Physiol Gastroi... - April 19, 2020 Category: Gastroenterology Authors: Hunt JE, Billeschou A, Windeløv JA, Hartmann B, Ullmer C, Holst JJ, Kissow H Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research