GSE126894 A TFAP2C Gene Signature is Predictive of Outcome in HER2 Breast Cancer (RNA-Seq)

Conclusions: Knockdown of TFAP2C with co-knockdown of CDH5 in SKBR-3 confirmed no significant effect on invasion, though there was a slight reduction in invasiveness with knockdown of CDH5 that failed to reach statistical significance (p=0.12). These findings support the conclusion that regulation of CDH5 and CDKN1A contribute to alterations of proliferation and invasiveness induced by knockdown of TFAP2C.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126894

Source: GEO: Gene Expression Omnibus - April 13, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research