Kutkoside-an iridoid glycoside, exerts anti-proliferative effects in drug-resistant human oral carcinoma cells by targeting PI3K/AKT signalling pathway, inducing apoptosis and suppressing cell migration and invasion.

CONCLUSION: Kutkoside shows potential anticancer and pro-apoptotic effects in HSC-2 oral carcinoma cells and as such may be developed as a possible anticancer agent provided further studies are performed. PMID: 32277652 [PubMed - as supplied by publisher]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research