Inflammasome activation by NLRP1 and NLRC4 in patients with coronary stenosis.

CONCLUSIONS: Inflammasome activation in atherosclerosis's patients can be systemic altered and may be triggered by NLRP1 and NLRC4 receptors. IL-1β gene expression was identified in our study as an important systemic detectable marker of plaque severity. PMID: 32276737 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32276737?dopt=Abstract

Source: Immunobiology - April 3, 2020 Category: Allergy & Immunology Authors: Borborema MEA, Crovella S, Oliveira D, de Azevêdo Silva J Tags: Immunobiology Source Type: research