Monitoring of radiologic disease activity by serum neurofilaments in MS

Conclusions
Low sNfL levels (≤30th percentile) help identify patients with MS with very low probability of recent radiologic disease activity during the preceding year. This result suggests that in future, sNfL assessment may substitute the need for annual brain MRI monitoring in considerable number (23.1%–36.4%) of visits in clinically stable patients.

Source: Neurology Neuroimmunology and Neuroinflammation - April 8, 2020 Category: Neurology Authors: Uher, T., Schaedelin, S., Srpova, B., Barro, C., Bergsland, N., Dwyer, M., Tyblova, M., Vodehnalova, K., Benkert, P., Oechtering, J., Leppert, D., Naegelin, Y., Krasensky, J., Vaneckova, M., Kubala Havrdova, E., Kappos, L., Zivadinov, R., Horakova, D., Ku Tags: MRI, Multiple sclerosis Article Source Type: research