Lifetime Methamphetamine Use Disorder and Reported Sleep Quality in Adults Living with HIV

This study evaluated whether a history of lifetime methamphetamine (MA) use disorder increases risk for poor sleep quality in people with or without HIV infection (HIV+/HIV −). Participants (n = 313) were stratified into four groups based on HIV status and lifetime MA use disorder diagnosis [HIV+/MA+ (n = 84); HIV+/MA− (n = 141); HIV−/MA+ (n = 16); and HIV−/MA− (n = 72)] and compared on global sleep outcomes using the Pittsburgh Sleep Qu ality Index (PSQI). Significant differences on global sleep were observed between HIV+/MA+ and HIV+/MA− groups, but not between the HIV− groups. Follow-up multiple regression analyses within the HIV+ subgroups examined global sleep scores as a function of MA status and clinical covariates, inclu ding those related to HIV disease and demographics. HIV+ individuals with a history of MA use disorder evidenced significantly poorer sleep quality and were more likely to be classified as problematic sleepers than those without a lifetime disorder. This was independent of depressed mood, body mass index, and viral suppression while on treatment. Poorer reported sleep quality among HIV+/MA+ was associated also with multiple adverse functional outcomes, including greater objective cognitive impairment, unemployment, clinical ratings of functional impairment, and self-reported cognitive difficul ties, decreased independence in activities of daily living, and poorer overall life quality. Interventions to avoid or curta...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research