An in vivo proton magnetic resonance spectroscopy study with optimized echo-time technique for concurrent quantification and T2 measurement targeting glutamate in the rat brain.

DISCUSSION: The results revealed that the quantification reliability of the OpQT2-Glu was comparable to that of the single short-TE MRS and its estimation reliability for the T2 relaxation time of glutamate was enhanced compared to the multiple TE MRS for T2 measurement. Despite certain limitations, the quantification and T2 estimation of glutamate can be concurrently performed within an acceptable scan time via high-field in vivo 1H MRS with the OpQT2-Glu.
PMID: 32246286 [PubMed - as supplied by publisher]

Source: Magma - April 2, 2020 Category: Radiology Authors: Yoo CH, Baek HM, Song KH, Woo DC, Choe BY Tags: MAGMA Source Type: research