Repeated anaphylaxis to cefuroxime in teenager and cross-reactivity to cephalosporins due to R2 side chain

Cephalosporins are one of the most prescribed classes of antibiotics1 and 1-3% of population report a cephalosporin allergy2. They are beta-lactam antibiotics and their chemistry, mechanism of action and toxicity are similar to penicillins. The most common classification of cephalosporins is by generation. There are five generations of cephalosporins.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research