Vitamin B12 is neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation

Bacterial meningitis (BM) causes apoptotic damage to the hippocampus and homocysteine (Hcy) accumulation to neurotoxic levels in the cerebrospinal fluid of children. The Hcy pathway controls bioavailability of...

Source: Journal of Neuroinflammation - April 1, 2020 Category: Neurology Authors: Karina Barbosa de Queiroz, Vanessa Cavalcante-Silva, Fl ávia Lombardi Lopes, Gifone Aguiar Rocha, Vânia D’Almeida and Roney Santos Coimbra Tags: Research Source Type: research