The impact of PCV7/13 on the distribution of carried pneumococcal serotypes and on pilus prevalence; 14  years of repeated cross-sectional surveillance.

CONCLUSIONS: Following PCV implementation, a dramatic and rapid decrease in VT strains prevalence was observed with a concomitant increase in non-VT strains. Piliated strains were nearly eliminated, yet re-emerged 7 years following PCV7/PCV13 implementation in various non-VT strains. This suggests that the pilus confers an advantage in colonization.
PMID: 32224005 [PubMed - as supplied by publisher]

Source: Vaccine - March 25, 2020 Category: Allergy & Immunology Authors: Kasher M, Roizin H, Cohen A, Jaber H, Mikhailov S, Rubin C, Doron D, Rahav G, Regev-Yochay G Tags: Vaccine Source Type: research