“Initial deterioration” upon intravenous methyl-prednisolon in myasthenia is multifactorial

With interest we read the article by Sugimoto et al. about a retrospective study on the “initial deterioration” of 51 patients with myasthenia gravis receiving 750–3000 mg/cycle intravenous methyl-prednisolone (IVMP) [1]. “Initial deterioration” was qualitatively and quantitatively defined, quantitatively as increase of two or more points on the myasthenia gravis activities of daily living (MG-ADL) score [1]. It was concluded that IVMP can be repeated after “initial deterioration” during a first cycle and that IVMP may lead to clinical improvement [1].

Source: Journal of the Neurological Sciences - March 30, 2020 Category: Neurology Authors: Josef Finsterer, Carla A. Scorza, Ana C. Fiorini, Fulvio A. Scorza Tags: Letter to the Editor Source Type: research