Do comorbid OCD-MDD patients need two separate dTMS protocols?

Major Depressive disorder (MDD) is the most common comorbidity with obsessive-compulsive disorder (OCD); more than 50% of OCD patients meet lifetime criteria for MDD or dysthymia[1]. Depression can significantly worsen OCD treatment outcomes[2] and elevate the risk for suicide[3]. While the multi-center-tested and FDA indicated deep transcranial magnetic stimulation (dTMS) treatment for OCD uses the H7 coil, to target dorsomedial prefrontal cortex (dmPFC) and anterior cingulate cortex (ACC)[4], the treatment for MDD uses the H1 coil to target the dorsolateral prefrontal cortex (dlPFC) bilaterally with preference to the left[5].

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 30, 2020 Category: Neurology Authors: Tal Harmelech, Aron Tendler, Yiftach Zangen, Abraham Zangen Source Type: research