Mechanism of murderous mushrooms paves path for parasitic helminth halt Genetics

“In the animal kingdom, the rule is, eat or be eaten” (ref. 1, p. 20). We will expand academic Thomas Szasz’s statement to include the fungi, because in the multifaceted interactions of fungi and nematodes, this is often a steadfast rule. Indeed, soil systems that appear inert or lifeless to...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Commentaries Source Type: research

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Conclusion. Most hematological and biochemical profiles were significantly lower in the Schistosoma mansoni-positive group as compared with the control group. Most hematological and biochemical profiles decline significantly as the parasite density increased. Hence, with Schistosoma treatment, supportive treatment against hematological and biochemical disorders is recommended. PMID: 32454838 [PubMed]
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
Authors: Njambi E, Magu D, Masaku J, Okoyo C, Njenga SM Abstract School children bear a significant burden of intestinal parasitic infections. Because they spend most of their time at home and school, it is necessary to identify the key water, sanitation, and hygiene (WASH) factors associated with these infections in both environments. This was a cross-sectional survey conducted in Mwea West, Kirinyaga County. 180 primary school children aged 8-14 years were randomly selected from three schools (Mianya, Mbui Njeru, and Mukou primary schools). Questionnaires and checklists were administered and single stool samples ...
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
Publication date: Available online 28 May 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Ying Zhu, Catherine Grueber, Yudong Li, Ming He, Lan Hu, Ke He, Honhyi Liu, Hemin Zhang, Honglin Wu
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Publication date: Available online 28 May 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Deak Georgiana, Gherman Călin Mircea, Ionică Angela Monica, Péter Áron, Sándor D. Attila, Mihalca Andrei Daniel
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Publication date: Available online 28 May 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Beric M. Gilbert, Milen Nachev, Maik A. Jochmann, Torsten C. Schmidt, Daniel Köster, Bernd Sures, Annemariè Avenant-Oldewage
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
The objective of this study was to determine the effectiveness of a therapeutic DNA vaccine containing T. cruzi genes in dogs with experimentally induced Chagas disease through clinical, pathological, and immunological analyses. Infection of Beagle dogs with the H8 T. cruzi strain was performed intraperitoneally with 3500 metacyclic trypomastigotes/kg body weight. Two weeks after infection, plasmid DNA immunotherapy was administered thrice at 15-day intervals. The clinical (physical and cabinet studies), immunological (antibody and cytokine profiles and lymphoproliferation), and macro- and microscopic pathological findings...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Authors: Frénal K, Krishnan A, Soldati-Favre D Abstract The phylum of Apicomplexa groups obligate intracellular parasites that exhibit unique classes of unconventional myosin motors. These parasites also encode a limited repertoire of actins, actin-like proteins, actin-binding proteins and nucleators of filamentous actin (F-actin) that display atypical properties. In the last decade, significant progress has been made to visualize F-actin and to unravel the functional contribution of actomyosin systems in the biology of Toxoplasma and Plasmodium, the most genetically-tractable members of the phylum. In addit...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
This report describes the clinical presentation, pathology and molecular diagnosis of canine parvovirus infection in male Boerboel and female Alsatian puppies. The history of the dogs was considered, examined clinically for vital parameters, haemogram changes and faeces screened for parasites and canine parvovirus faecal antigen. Tissue samples were taken at necropsy for confirmatory diagnosis using histopathology, immunohistochemistry, polymerase chain reaction (PCR) and sequence analysis. There was a severe regenerative anaemia, leucopenia and lymphopaenia. The positive antigen faecal test and pathological findings of ha...
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research
ConclusionThe route of infection in our patient was unclear but is likely to have been orofecal. Neither her infection nor its treatment caused a deterioration in her renal function.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
AbstractRelevanceIvermectin, as an old anti-parasite drug, can suppress almost completely the growth of various human cancers, including ovarian cancer (OC). However, its anticancer mechanism remained to be further studied at the molecular levels. Ivermectin-related molecule-panel changes will serve a useful tool for its personalized drug therapy and prognostic assessment in OCs.PurposeTo explore the functional significance of ivermectin-mediated lncRNA-EIF4A3-mRNA axes in OCs and ivermectin-related molecule-panel for its personalized drug therapy monitoring.MethodsBased on our previous study, a total of 16 lncRNA expressi...
Source: EPMA Journal - Category: International Medicine & Public Health Source Type: research
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