Quality over quantity: skeletal loading intensity plays a key role in understanding the relationship between physical activity and bone density in postmenopausal women

Conclusion: Despite having higher-than-expected PA, the low stepping loads observed in this cohort, along with half of the participants having low BMD measures, underscores the need for PA intensity to be considered in the management of postmenopausal bone health.
Source: Menopause - Category: OBGYN Tags: Original Studies Source Type: research

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Conclusions: This study suggested that lower BMD and increased loss rate of BMD were associated with a higher risk of carotid calcification plaques in Chinese postmenopausal women. PMID: 31612731 [PubMed - as supplied by publisher]
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Given that resistance training is shown to reduce mortality in older individuals, it makes sense that we would see the opposite effect when looking at low muscle mass in limbs. Skeletal muscle isn't an inert tissue, being quite involved in insulin metabolism, for example, and exercise has all sorts of interesting effects on the operation of metabolism, such as upregulation of beneficial cellular stress response mechanisms. Aging is associated with a progressive loss of muscle mass and strength, with the loss of stem cell activity being a leading cause. This ultimately results in frailty and the condition of weakness known ...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
In conclusion, osteoporosis is prevalent among RA patients, as a part of a complex transformation of body mass composition, involving BMI and fat mass. The novel QUS scanning technique was able to replicate the results of the established DXA measurement of BMD and is potentially suitable for screening wide populations for osteoporosis. PMID: 31410123 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Objective: The aim of the study was to evaluate the predictive ability of obesity indices derived by dual-energy x-ray absorptiometry (DXA) regarding coronary heart disease (CHD). Methods: DXA total body scans were performed on 71 consecutive postmenopausal women who were referred for myocardial perfusion imaging (MPI). Twenty-four women with CHD diagnosed by MPI were considered as cases, whereas the remaining 47 women with normal MPI results were considered as controls. Biochemical markers, body mass index (BMI) and waist circumference (WC) were also recorded for all women and correlated to DXA adiposity indices. Rec...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
Influence of Habitual Physical Behavior – Sleeping, Sedentarism, Physical Activity – On Bone Health in Community-Dwelling Older People Gladys Onambele-Pearson1*, Jorgen Wullems1,2, Conor Doody1, Declan Ryan1,3, Christopher Morse1 and Hans Degens4,5,6 1Department of Exercise and Sport Science, Manchester Metropolitan University, Manchester, United Kingdom 2Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium 3Faculty of Health and Society, University of Northampton, Northampton, United Kingdom 4School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom 5In...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusions Patients with CP are at increased risk of low BMD, which is likely multifactorial. Hypogonadism, possibly related to opioid pain medications, may be an independent risk factor for low BMD in CP.
Source: Pancreas - Category: Gastroenterology Tags: Original Articles Source Type: research
This study tested whether high-intensity interval training is a time-efficient strategy for improving visceral adiposity tissue and inflammatory markers in obese postmenopausal women when compared with combined training. Moreover, we tested whether change in visceral adiposity tissue is associated with alterations in these inflammatory markers. Methods: Postmenopausal women were randomized in two groups: combined training (n = 13) and high-intensity interval training (n = 13). The combined training group performed 60 minutes of walking at 70% of maximum heart rate and resistance exercises at 70% of one repetitio...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
We present the 10-year results of the ReCap Magnum HRA system in a consecutive single surgeon's series from a non-designer centre. PATIENTS AND METHODS:: Hip resurfacing arthroplasty (HRA) was performed in active males under 65 years and in pre-menopausal females with adequate bone density proven by a DEXA scan. Clinical follow-up; annual Oxford hip scoring, UCLA scoring and whole blood metal ion level measurement. Kaplan-Meier method was used to determine survivorship with revision as the end point. Radiographs were analysed for; acetabular inclination, notching, neck thinning and change in implant position. 7...
Source: Hip International - Category: Orthopaedics Authors: Tags: Hip Int Source Type: research
z-López FR Abstract OBJECTIVE: The study aimed to determine the impact of age, age at menopause, body mass index (BMI), and lumbar and hip bone mineral density (BMD) on muscle strength in young postmenopausal women with normal vitamin D levels. METHODS: This was a cross-sectional study performed in 392 postmenopausal women aged
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
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