Real-world assay variability between laboratories in monitoring of recombinant factor IX Fc fusion protein activity in plasma samples.

CONCLUSION: This large, real-world data set indicates that rFIXFc activity in plasma samples can be accurately measured with the majority of routine OSC and CS assay methods. Given the variation in FIX assay procedures between sites, it is important that individual laboratories qualify their in-house methods for monitoring of rFIXFc activity.
PMID: 32202380 [PubMed - as supplied by publisher]

Source: International Journal of Laboratory Hematology - March 22, 2020 Category: Hematology Authors: Sommer JM, Sadeghi-Khomami A, Barnowski C, Wikén M, Willemze AJ Tags: Int J Lab Hematol Source Type: research