Oligometastatic Disease and Local Therapies: A Medical Oncology Perspective.

This article reviews the literature in oligometastatic disease and considers a theoretical rationale for a curative approach in a subset of oligometastatic solid tumor patients. In oligometastatic colorectal cancer patients with liver-only metastases and in non-small cell lung cancer patients with disease control after primary therapy and with limited nodal involvement, aggressive local therapies should be considered. Clinical trials and further biomarker validation across disease types are necessary to clarify which subsets of patients may define a theorized "oligometastatic state" and therefore benefit from aggressive local therapies.
PMID: 32205539 [PubMed - in process]

Source: Cancer Journal - February 29, 2020 Category: Cancer & Oncology Authors: Hafez N, Gettinger S Tags: Cancer J Source Type: research