Illustration of tessellation in Down syndrome.

Conclusions: Mechanical stretching of the choroid could explain the high rate of tessellation in myopes. Other factors must contribute to the higher prevalence of tessellated fundus in children with Down syndrome without myopia. We discuss potentially relevant factors and propose vascular involvement as a contributor to tessellation in our population with Down syndrome. Further studies assessing choroidal vasculature in individuals with Down syndrome are needed to confirm this theory. PMID: 32200669 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32200669?dopt=Abstract

Source: Ophthalmic Genetics - March 25, 2020 Category: Opthalmology Tags: Ophthalmic Genet Source Type: research