Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography

This study aimed to explore the associations between Cer and culprit plaque characterizations evaluated by optical coherence tomography (OCT). It was found that plasma Cer are associated with culprit plaque vulnerability evaluated by OCT, providing evidence supporting proatherogenic roles and potential to act as markers for plaque vulnerability of Cer.Graphical AbstractWith increasing plasma ceramide levels, the prevalence of thin-cap fibroatheroma (TCFA) and plaque rupture (PR) is higher, that is, culprit plaques are more vulnerable.
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research