Targeting of externalized αB-crystallin on irradiated endothelial cells with pro-thrombotic vascular targeting agents: Potential applications for brain arteriovenous malformations

This study explored αB-crystallin (CRYAB) as a radiation induced target and pre-tested the specificity and efficacy of a CRYAB-targeting coaguligand for in vitro thrombus induction.

Source: Thrombosis Research - March 16, 2020 Category: Hematology Authors: Sinduja Subramanian, Zhenjun Zhao, Fahimeh Faqihi, Georges E. Grau, Valery Combes, David W. Inglis, Vaughan Moutrie, Marcus A. Stoodley, Lucinda S. McRobb Tags: Full Length Article Source Type: research