Thrombospondin-1 mediates muscle damage in brachio-cervical inflammatory myopathy and systemic sclerosis

Conclusions
Patients with SSc may present with a clinically and pathologically distinct myopathy. A prompt and correct diagnosis has important implications for treatment. Finally, TSP-1 may participate in the pathologic changes observed in muscle.

Source: Neurology Neuroimmunology and Neuroinflammation - March 5, 2020 Category: Neurology Authors: Suarez-Calvet, X., Alonso-Perez, J., Castellvi, I., Carrasco-Rozas, A., Fernandez-Simon, E., Zamora, C., Martinez-Martinez, L., Alonso-Jimenez, A., Rojas-Garcia, R., Turon, J., Querol, L., de Luna, N., Milena-Millan, A., Corominas, H., Castillo, D., Corte Tags: MRI, All Neuromuscular Disease, Muscle disease Article Source Type: research