THE action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis.

In conclusion, Th17 cells can efficiently cross the BBB using pathways distinct from those used by Th1 cells, leading to BBB disruption, the activation of other inflammatory cells and neurodegeneration in MS patients.
PMID: 32122685 [PubMed - as supplied by publisher]

Source: Human Immunology - February 27, 2020 Category: Allergy & Immunology Authors: Balasa R, Barcutean L, Balasa A, Motataianu A, Roman-Filip C, Manu D Tags: Hum Immunol Source Type: research