Acquired resistance to cetuximab is associated with the overexpression of Ras family members and the loss of radiosensitization in head and neck cancer cells

Conclusion: Targeting Ras and PI3K activity improves the outcome of irradiation in cetuximab-resistant HNSCC cell lines in vitro.

Source: Radiotherapy and Oncology - July 29, 2013 Category: Radiology Authors: Mohammad Saki, Mahmoud Toulany, H. Peter Rodemann Tags: Original Articles Source Type: research