Evaluation of inflammatory bowel disease activity in children using serum trefoil factor peptide.

CONCLUSIONS: TFF3 level increased with CD activity, which is of significance for diagnosis and for evaluation of mucosal healing. TFF3 could also be a marker in pediatric UC, as TFF3 positively correlated with UCAI. IMPACT: The diagnosis and evaluation of IBD is difficult; endoscopy provides objective assessment; TFF3 can be a useful marker instead of endoscopy.TFF3 was increased in active CD of children; TFF3 can be used as a clinical marker of pediatric CD; TFF3 can diagnose and evaluate mucosal healing of CD.Pediatrician should pay attention to clinical marker; TFF3 level may be a key evaluation of mucosal healing of CD; the value of diagnosis of TFF3 in CD is important. PMID: 32120375 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32120375?dopt=Abstract

Source: Pediatric Research - March 1, 2020 Category: Pediatrics Authors: Teng X, Yang Y, Liu L, Yang L, Wu J, Sun M, Xu L Tags: Pediatr Res Source Type: research