Anemia and iron deficiency in Crohn's disease.

Anemia and iron deficiency in Crohn's disease. Expert Rev Gastroenterol Hepatol. 2020 Feb 20;: Authors: Yue Ying C, Jun S, Yu Fan W, Hua RZ Abstract Introduction: Anemia is a common extraintestinal complication of Crohn's disease (CD) mainly caused by iron deficiency and, affects the quality of life of CD patients. In recent years, the etiology and pathology of iron-deficiency anemia (IDA) and anemia of chronic diseases have been elucidated. However, common biochemical parameters of iron status for the assessment of patients with anemia and CD are insufficient. Thus, novel iron indices are required for accurate assessment in CD patients with IDA. Oral iron supplementation as IDA treatment is common and associated with minor gastrointestinal side effects. Intravenous substitution improves safety profiles but may not be tolerable in some patients. Fortunately, additional therapies for anemia in active CD have emerged in recent years.Area covered: In this review, the authors explore the link among anemia, iron deficiency, and CD. Furthermore, the authors discuss the current diagnosis and therapy for anemia and iron deficiency in CD and propose new directions for future research.Expert opinion: Exploring the pathogenesis and treatments of anemia and iron deficiency in CD may lead to the development of potential tools for the early diagnosis and effective treatment of anemia in CD patients and improve their quality of life. PMID: ...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research