Bioprospecting of novel therapeutic agents from marine bacterium; Serratia marcescens

Publication date: Available online 20 February 2020Source: Materials Today: ProceedingsAuthor(s): Asha Gangadharan, Jismy Jolly, Nayomi JohnAbstractBioprospecting is the searching of novel bioactive natural products from unexplored natural environment. The aim of the study was to isolate novel therapeutic agents from marine bacterium. The marine bacterium was identified as Serratia marcescens using molecular identification methods. The secondary metabolites were extracted and showed single spot on TLC at Rf of 0.74. The metabolite showed good antioxidant and antibacterial activity against Staphylococcus aureus, pseudomonas sp, E. coli, Klebsiella sp, Salmonella paratyphi A. The antielastase activity was appreciable when compared to standard elastase inhibitor. The structural characterization of purified metabolite by GC-MS revealed 2,4-ditert butylphenol as major component.
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research

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Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
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Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
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