LncRNA MEG3 targeting miR-424-5p via MAPK signaling pathway mediates neuronal apoptosis in ischemic stroke.

In conclusion, it was demonstrated that MEG3 accelerated the process of IS by suppressing miR-424-5p, which targeted Sema3A and the activated MAPK pathway. These results might provide useful information for exploring the potential therapeutic targets in IS. PMID: 32065781 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32065781?dopt=Abstract

Source: Aging - February 15, 2020 Category: Biomedical Science Authors: Xiang Y, Zhang Y, Xia Y, Zhao H, Liu A, Chen Y Tags: Aging (Albany NY) Source Type: research