Dexmedetomidine pretreatment improves lipopolysaccharide-induced iron homeostasis disorder in aged mice.

CONCLUSION: Dexmedetomidine has no effect on iron metabolism pathway, but it can improve the cognitive decline and the iron disorder by reducing neuroinflammation and oxidative stress. The research indicates that dexmedetomidine plays a neuroprotective role.
PMID: 32065090 [PubMed - as supplied by publisher]

Source: Current Neurovascular Research - February 15, 2020 Category: Neurology Authors: Guo F, Kang J, Tan J, Wang Y, Jia L, Xu H Tags: Curr Neurovasc Res Source Type: research