Determinants of Reversibility of Beta-cell Dysfunction in response to Short-term Intensive Insulin Therapy in Patients with early Type 2 Diabetes.
In conclusion, decline in HOMA-IR may be a key determinant of improvement of beta-cell function in response to short-term IIT, suggesting a fundamental contribution of insulin resistance to the reversible component of beta-cell dysfunction in early T2DM.
PMID: 24129396 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Endocrinology and Metabolism - Category: Physiology Authors: Kramer CK, Choi H, Zinman B, Retnakaran R Tags: Am J Physiol Endocrinol Metab Source Type: research
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